Venezuela, 28 de Agosto de 2008

Año 2008, Volumen 58 - Número 1
Año 2008, Volumen 58
Número 1


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HOME > EDICIONES > Año 1998, Volumen 48 - Número 3

Trabajos de Investigación
Diferencias en la composición porcentual de los poliinsaturados de cadena larga en eritrocitos materno-fetales en nacimientos de término o pretérmino en humanos

Julia Araya Araya, Myrna Rojas García, Pilar Fernández Fraile, Argentina Mateluna Acevedo
Universidad de Chile y Maternidad Hospital San José.

SUMMARY
Maternal and fetal long chain fatty acids in term and preterm birth

The content and distribution of long-chain polyunsaturated fatty acids (LCP) of maternal-fetal erythrocytes phospholipids was investigated. Blood samples from healthy pregnant women were taken from maternal veins and umbilical cord al spontaneous deli very time. Two groups were segregated and compared in terms of fetuses gestational age: preterm delivery (32-34 weeks) and term delivery (40 weeks). The results showed that in erythrocytes of term newborn the content of LCP omega 6 and omega 3; particularly 20:4w6 (ARA) and 22:6w3 (DHA), were found to be statistically higher than their respective mother. However, in preterm newboms, all LCP from phospholipids erythrocytes were found to be statistically lower than intheir mother. Comparing the content of ARA and DHA between the newborn groups, it observed thatonly DHA was decreased in preterm group. Women who delivered premature babies showed a blood ratio ARA/DHA higher than those who delivered term-babies. From this study and considering previous information it can be suggested that a high content of ARA and ARA/DHA ratio in maternal and fetal erythrocytes mar considered an early risk signal of preterm delivery.

Key words: Arachidonic, docosahexaenoic, maternal-fetal erythrocytes, preterm birth.



Recibido: 18/09/1997
Aceptado: 20/07/1998



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