Venezuela, 7 de Octubre de 2008

Año 2008, Volumen 58 - Número 1
Año 2008, Volumen 58
Número 1


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HOME > EDICIONES > Año 2001, Volumen 51 - Suplemento 1

Artículos Originales
The chemistry of ferrous bis-glycinate chelate

Stephen D. Ashmead
Albion Laboratories, Inc., Clearfield, Utah U.S.A.

SUMMARY
The chemistry of ferrous bis-glycinate chelate

In order to produce a ferrous chelate tour criteria 1 must be met: 1) the ligand must contain two functional groups which are capable of entering into covalent and coordinate covalent bonds; 2) a ring structure with the ferrous ion being the closing member of the ring must be created; 3) the chelate must be (sterically possible; and 4) the chelation reaction must be energetically possible. In addition to the above, a totally nutritionally functional ferrous chelate must meet three further criteria: 1) it must have low molecular weight; 2)its stability constant must be nutritionally functional; and 3) the ligand must be metabolizable by the body. When. ferrous iron is reacted with glycine and forms a bis-glycinate chelate, it meets all of the requirements of being both a chelate and being a totally nutritionally functional chelate.

Key words: Chelation, criteria for chelation, Ferrochel, amino acid chelates.






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