Venezuela, 8 de Febrero de 2012

Año 2011, Volumen 61 - Número 3
Año 2011, Volumen 61
Número 3


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HOME > EDICIONES > Año 2004, Volumen 54 - Número 3

Trabajos de Investigación
Lipemia postprandial en adultos jóvenes de diferentes etnias en Colombia

Cecilia Aguilar de Plata1 , Maria Teresa Velasco de Echeverri2, Beatriz Gracia de Ramírez3, Alberto Pradilla Ferreira4, Martha Liliana Cruz Naranjo5, Mildrey Mosquera Escudero6
Departamento de Ciencias Fisiológicas. Universidad del Valle. Colombia 1,2,6, Departamento de Pediatría. Universidad del Valle. Colombia3, Escuela de Salud Pública. Universidad del Valle. Colombia4, Departamento de Medicina Preventiva. Universidad de California del Sur. Estados Unidos de América5

SUMMARY
Postprandial lipemia in colombian young adults from different ethnias

Postprandial lipemia has been associated with atherogenesis an other non infectious chronic diseases. A descriptive, non aleatory study of 51 healthy young adults (23.8 ± 4 years) of different ethnic background was carried out to identify possible personal or life style factors associated with the response of plasma lipids after a mixed carbohydrate and lipid load. Personal, family, life styles including use of drugs and activity and ethnic background were recorded. Anthropometrical measurements, a short insulin and postprandial lipemia tests were done. From these observations body mass index (BMI) and area under the curve (AUC) for lipids and glucose were calculated. High mean values were observed in AUC for glucose, triacylglycerol and nonesterified fatty acids (NEFA). Postprandial glucose with differences by age (p=0.05 Bonferroni) but no ethnic, gender, BMI or insulin sensitivity related significant differences were found. Mestizos (40%) showed two, and Negroes three (27%) postprandial triglyceridemia peaks. Noteworthy, subjects presenting four peaks had elevated BMI. Higher triglyceridemia values were found in white and mestizos (p<0.05), in subjects older than 29 and in males(p<0.05). Statistical correlation (r2=0.70) between BMI and triglyceridemia and change in postprandial trigliceridemia was found in white and black subjects. NEFA declined up to the second hour, but at 6-7 hours they reached levels higher than base values. Higher than reported values for UCA and BMI and an abnormal response to fat intake with an early release of NEFA was found. The high correlation between BMI and postprandial trigliceridemia suggests that body mass index could be a good predictor of postprandial trigliceridemia.

Key words: Postprandial lipemia, ethnic, risk factors, chronic no transmitted diseases, postprandial glicaemia.



Recibido: 20/10/2003
Aceptado: 08/07/2004



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