HOME > EDICIONES > Año 2006, Volumen 56 - Número 4
Trabajos de Investigación
Niveles séricos de homocisteína total y lipoproteínas en adultos jóvenes de áreas rurales y urbanas de Costa Rica
Ileana Holst-Schumacher, Rafael Monge-Rojas, Mauro Barrantes-Santamaría
Facultad de Microbiología y Centro de Investigación en Hematología y Trastornos Afines (CIHATA), Universidad de Costa Rica, Instituto Costarricense de Investigación y Enseñanza en Nutrición y Salud (INCIENSA), Oficina de Bienestar y Salud, Universidad de Costa Rica
|
SUMMARY
Serum total homocysteine and lipoproteins levels in young adults from urban and rural areas of Costa Rica
This study evaluated the lipid profile and the serum levels of total homocysteine of 400 adults aged 20 to 40 years, residents of rural and urban areas of the central valley of Costa Rica. The results showed that the proportion of subjects from urban areas with high levels of LDL-C (= 4,13 mmol/L) was 11% higher than the proportion of adults from rural areas (29,2% y 18,0%, p=0,045). On the contrary, the proportion of rural subjects with low HDL-C levels (< 1,03 mmol/L) was higher 19% than the proportion of urban adults (56,0% y 75,3%, p=0,001). Rural residents also showed higher serum levels of triglycerides and total homocysteine than the urban residents, although the differences were not significant (TG: 1,94 mmol/L y 2,02 mmol/L, p=0,529; TH: 9,33 µmol/L y 9,84 µmol/L, p=0,145). The prevalences of hyperhomocysteinemia (>15 mmol/L), hypercholesterolemia (= 5,17 mmol/L) and hypertriglyceridemia (= 1,69 mmol/L) in the studied population were 5,8%, 53,6% y 50,1% respectively. 82% of the studied population had LDL-C levels above 2,58 mmol/L and approximately 61% of the adults had HDL-C levels lower than 1,03 mmol/L. Our data suggest that the studied costarrican population has a very high cardiovascular risk. The prevalence of low levels of HDL-C (< 1,03 mmol/L), marginal levels of total homocysteine and a tendency to have high levels of triglycerides were the most outstanding cardiovascular risk factors found in this population, specially in rural subjects, which could be associated with the quality of the diet of these habitants. It is necessary to develop effective intervention strategies to promote healthy lifestyles in the population in order to reduce the cardiovascular mortality rates in Costa Rica.
Key words: Lipid profile, cholesterol, triglycerides, cardiovascular disease, total homocysteine.
Recibido: 18/08/2006
Aceptado: 31/01/2007
 |
PRIVACIDAD | ACCESIBILIDAD
ALAN-VE ISSN 0004-0622 - Depósito Legal: pp 199602DF83
Sociedad Latinoamericana de Nutrición
Producción editorial en Venezuela: Capítulo Venezolano - RIF: J-30843129-0
Urbanización Santa María, primera transversal, No. 417-214, Planta Alta
Tele-Fax: (+58-212) 283.8618
E-mail info@alanrevista.org
Código Postal: 1070
Caracas - Venezuela |
|
|
Ir al principio