Comunicaciones Orales

CO037. ASSESSMENT OF ENERGY METABOLISM IN PATIENTS WITH SHORT BOWEL SYNDROME USING THE DOUBLY LABELED WATER METHOD

Priscila Fassini1, Eduardo Ferriolli1, Júlio Marchini1, Karina Pfrimer1

1 University of São Paulo, Brasil.

Introduction: The short bowel syndrome (SBS) is one of the most serious and severe malabsorption state and the dietetic therapy is an important challenge to be faced. Objective: The aim was to compare the total energy expenditure (TEE) measured by the doubly labeled water (DLW) method with its estimated by predict formula. Methods: Were evaluated 11 volunteers (6 women, 5 men) with SBS and a control group (CG) with volunteers without SBS, with similar characteristics (gender, age, ethnicity, BMI) of SBS group. Physical activity level was performed with activPALTM monitor for 14 days. Resting energy expenditure (REE) measured by indirect calorimetry (IC) and estimated by Harris-Benedict. TEE measured (DLW) multi-point method was compared with predicted by Escott-Stump (2002). To compare the methods of predicted versus measured energy expenditure was used T-test and Bland-Altman in each group (p < 0.05). Results: The age was 53±8 years for both groups. REE showed no significant differences between the groups and methods. Measured REE (IC) was 1,347±193 kcal/d; 1,369±196 kcal/d and Predicted REE (Harris-Benedict) was 1,265±127 kcal/d; 1,281±104 for SBS and GC groups, respectively. The number of steps/day was significantly different: 6,632±2,302 steps/day for SBS and 10,386±3,671 steps/day for CG. Predicted TEE did not differ signi?cantly between the groups: 1,517±175 kcal/d for the SBS, 1,522±171 kcal/d for GC. However, measured TEE (DLW) was significantly different: 1,835±276kcal for SBS and 2,396±448kcal for CG. The comparison between the methods showed a signi?cantly difference (p=0.01; p<0.01) respectively for SBS and GC. Conclusions: TEE differ between groups when analyzed by the DLW, which could be due to the profile of physical activity by number of steps per day. The determination of energy expenditure can be underestimate when calculated by predicted equations in comparison with the DLW method, which may be inadequate, affecting negatively the evolution of these patients.